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Stephen WoodingAssistant ProfessorThe McDermott Center for Human Growth and DevelopmentUniversity of Texas Southwestern Medical Center Simmons Biomedical Research Bldg., 10th floor 6000 Harry Hines Blvd. Dallas, TX 75390-8591   Phone: +1-214-648-1424 Fax: +1-214-648-1666   Email: stephen.wooding@utsouthwestern.edu |
Education and Employment
2006-Pres. - Assistant Professor (Human Genetics), University of Texas Southwestern Medical Center
2005-2006 - Research Assistant Professor (Human Genetics), University of Utah
2002-2005 - Kirschstein Postdoctoral Fellow (Human Genetics), University of Utah
1998-2001 - Ph.D. (Anthropology), University of Utah
1992-1996 - M.S. (Biology), University of Utah
1988-1992 - B.A. (Biology), University of Colorado
Research
My research is focused on two main questions: 1) How have population history and natural selection have interacted to produce patterns of genetic variation?, and 2) How can information about population history and natural selection be used in the dissection of genotype-phenotype correlations? My lab investigates these questions using a combination of empirical, theoretical, and computational methods to analyze patterns of diversity in populations around the world. Over the years, we have worked on many different genes in many different organisms, including bears, viruses, and even chimpanzees; however, our current emphasis is on patterns of variability in genes controlling taste perception in humans.
Publications
Here are some of my recent papers. (A complete list of my publications, along with reprints, is on this page. Most of my publications are also listed in PubMed.)Software
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Wooding, S., Bufe, B., Grassi, C., Howard, M.T., Stone, A.C., Vazquez, M., Dunn, D.M., Meyerhof, W., Weiss, R.B., Bamshad, M.J. 2006. Independent evolution of bitter-taste sensitivity in humans and chimpanzees. Nature 440:930-934. [REPRINT] ![]()
Wooding, S., Stone, A. C., Dunn, D. M., Jorde, L. B., Weiss, R. K., Ahuja, S., Bamshad, M. J. 2005. Contrasting effects of natural selection on human and chimpanzee CC chemokine receptor 5. American Journal of Human Genetics 76:291-301. [REPRINT] ![]()
Wooding, S., Kim, U.-k., Bamshad, M. J., Larsen, J., Jorde, L. B., Drayna, D. 2004. Natural selection and molecular evolution in PTC, a bitter taste receptor gene. American Journal of Human Genetics 74:637-646. [REPRINT] ![]()
Jorde, L. B., Wooding, S. 2004. Human genetic variation and "race". Nature Genetics 36:S28-S33. [REPRINT] ![]()
Bamshad, M., Wooding, S. 2003. Signatures of natural selection in the human genome. Nature Reviews Genetics 4:99-111. [REPRINT]
PhotographsSneato - Software for inferring and drawing haplotype networks.
DFSC - This program tests Tajima's D and Fu and Li's D, D*, F, and F* statistics under the assumption that population size has changed over time.
TreeToy - Simulation of Genealogical Coalescence.
Cuba
Salt Lake City